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Main information about Allopurinol


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Allopurinol Identifier:
The route of administration ORAL
The active ingredient list ALLOPURINOL
The pharmacological class category Xanthine Oxidase Inhibitor [EPC],Xanthine Oxidase Inhibitors [MoA]

National Drug Code (NDC) The trade name The active ingredient(s) The dosage form The start date Name of Company Strength Number and Unit
0378-0137 Allopurinol allopurinol TABLET 19861024 Mylan Pharmaceuticals Inc. 100mg/1
0378-0181 Allopurinol allopurinol TABLET 19861024 Mylan Pharmaceuticals Inc. 300mg/1
0591-5543 Allopurinol Allopurinol TABLET 20090406 Watson Laboratories, Inc. 100mg/1
0591-5544 Allopurinol Allopurinol TABLET 20090406 Watson Laboratories, Inc. 300mg/1

Full Allopurinol Identification


Allopurinol is indicated for the treatment of hyperuricemia associated with primary or secondary gout.
Allopurinol is indicated to treat gout, high levels of uric acid in the body caused by certain cancer prescription, and kidney stones. Allopurinol is in a class of prescription called xanthine oxidase inhibitors. It works by reducing the production of uric acid in the body. High levels of uric acid may cause gout attacks or kidney stones. Allopurinol is indicated to prevent gout attacks, not to treat them once they occur.

A xanthine oxidase inhibitor that decreases uric acid production. It acts as an antimetabolite on some simpler organisms.


Patients who have developed a severe reaction to allopurinol should not be restarted on the drug.


Allopurinol comes as a tablet to take by mouth. It is usually taken once or twice a day, preferably after a meal. To help you remember to take allopurinol, take it around the same time every day.

Your doctor will probably start you on a low dose of allopurinol and gradually increase your dose, not more than once a week.

It may take several months or longer before you feel the full benefit of allopurinol. Allopurinol may increase the number of gout attacks during the first few months that you take it, although it will eventually prevent attacks. Your doctor may prescribe another prescription such as colchicine to prevent gout attacks for the first few months you take allopurinol.

Allopurinol, a structural analog of the natural purine base hypoxanthine, is indicated to prevent gout and renal calculi due to either uric acid or calcium oxalate and to treat uric acid nephropathy, hyperuricemia, and some solid tumors.

Side Effects

Allopurinol side effects that you should report to your health care professional or doctor as soon as possible:
- blood in the urine;
- diarrhea;
- drowsiness;
- fever, sore throat, chills, and other signs of infection;
- irritation of the eyes;
- itching;
- loss of appetite;
- painful urination;
- skin rash;
- swelling of the lips or mouth;
- unexpected weight loss;
- upset stomach;
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