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Main information about Felodipine


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Felodipine Identifier:
The route of administration ORAL
The active ingredient list FELODIPINE
The pharmacological class category Calcium Channel Antagonists [MoA],Dihydropyridine Calcium Channel Blocker [EPC],Dihydropyridines [Chemical/Ingredient]

National Drug Code (NDC) The trade name The active ingredient(s) The dosage form The start date Name of Company Strength Number and Unit
0186-0450 PLENDIL Felodipine TABLET, EXTENDED RELEASE 19941004 AstraZeneca LP 41396mg/1
0186-0451 PLENDIL Felodipine TABLET, EXTENDED RELEASE 19910916 AstraZeneca LP 5mg/1
0186-0452 PLENDIL Felodipine TABLET, EXTENDED RELEASE 19910916 AstraZeneca LP 10mg/1
0378-5011 Felodipine Felodipine TABLET, FILM COATED, EXTENDED RELEASE 20130328 Mylan Pharmaceuticals Inc. 41396mg/1

Full Felodipine Identification


Felodipine is indicated for the treatment of hypertension and angina.
Felodipine is indicated to treat high blood pressure. It relaxes your blood vessels so your heart does not have to pump as hard.

A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.


Felodipine is contraindicated in patients who are hypersensitive to this product.


Felodipine comes as a tablet to take by mouth. It is usually taken once a day. Do not crush, chew, or divide felodipine tablets.

Felodipine controls high blood pressure but does not cure it.

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Side Effects

Felodipine side effects that you should report to your health care professional or doctor as soon as possible:
- constipation;
- difficulty breathing or swallowing;
- dizziness or lightheadedness;
- enlargement of gum tissue around teeth;
- fainting;
- fast heartbeat;
- flushing (feeling of warmth);
- headache;
- heartburn;
- rash;
- swelling of the face, eyes, lips, tongue, arms, or legs;
- weakness;
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